A novel class of meso-tetrakis-porphyrin derivatives exhibit potent activities against hepatitis C virus genotype 1b replicons in vitro
نویسندگان
چکیده
To whom correspondence should be addressed: Department of Pharmacology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06520. E-mail: [email protected]. Copyright © 2009, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. Antimicrob. Agents Chemother. doi:10.1128/AAC.01206-09 AAC Accepts, published online ahead of print on 9 November 2009
منابع مشابه
A novel class of meso-tetrakis-porphyrin derivatives exhibits potent activities against hepatitis C virus genotype 1b replicons in vitro.
Recent years have seen the rapid advancement of new therapeutic agents against hepatitis C virus (HCV) in response to the need for treatment that is unmet by interferon (IFN)-based therapies. Most antiviral drugs discovered to date are small molecules that modulate viral enzyme activities. In the search for highly selective protein-binding molecules capable of disrupting the viral life cycle, w...
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